Lora Kasselman, PhD
I bring more than 19 years of academic and pharmaceutical research experience, with a special focus on general and neurovascular inflammation, to my role as a research scientist at NYU Langone Hospital—Long Island. During and after my doctoral training in neuropsychology, I conducted research on vascular inflammation in diseases such as scleroderma and peripheral neuropathy.
Throughout the years I have gained extensive experience in designing and conducting behavioral experiments. I have many years of involvement in analysis using histological and molecular techniques, including immunohistochemistry and protein detection.
Currently, I conduct cell culture experiments to determine the molecular mechanisms that drive differential risk for cardiovascular disease in autoimmunity. Part of this work involves identifying signature microRNAs that may explain elevated cardiovascular risk, including the identification of gut–microflora-related microRNAs.
I recently published a review paper in Atherosclerosis, which suggests that gut dysbiosis-related microbial byproducts may underlie an increased risk for cardiovascular disease across several disease states, including rheumatoid arthritis, systemic lupus erythematosus, obesity, and type 1 diabetes.
I’m also involved in a project with researchers from NYU Langone Hospital—Long Island’s Department of Biostatistics that uses data from the National Health and Nutrition Examination Survey to examine the association between the consumption of fermented foods and cognitive function.
We have identified a positive association between the consumption of fermented foods and higher performance on cognitive subtests in children, when stratified by ethnicity. In order to pursue the mechanistic possibilities that this relationship presents, I initiated laboratory research using an in vitro model of brain cells. Based on preliminary results, I wrote and submitted to the Nature Research Awards Global Grants for Gut Health program a grant titled “Extracellular Vesicles: A Link Between Gut Microbiota and Cognitive Function?”
Other collaborators include NYU Langone Hospital—Long Island clinicians from the Divisions of Gastroenterology, Hepatology, Nutrition, Behavioral Health, and Geriatrics. In addition to research, I routinely mentor house staff and train residents and fellows in experimental design and research techniques related to molecular biology.
Education and Training
- Postdoctoral Fellowship, Penn State College of Medicine, Neural and Behavioral Science, 2011
- Postdoctoral Fellowship, Beth Israel Deaconess Medical Center, Harvard Medical School, Neurology, 2009
- PhD, The Graduate Center, City University of New York, Neuropsychology, 2006
- MS, New York Medical College, Microbiology and Immunology, 2002
- BS, Penn State University, General Science, 1996
NYU Langone Hospital—Long Island
Research and Academic Center
101 Mineola Boulevard, Floor 4
Mineola, NY 11501