At NYU Grossman Long Island School of Medicine, the Departments of Psychiatry is committed to research that drives the discovery of new approaches to behavioral healthcare. Our efforts span biomedical research, psychopharmacology, sociocultural analyses, and more.

A Human Co-Culture Model of Alzheimer’s Disease as Biomarker and Predictor of Treatment Response

In partnership with the Departments of Medicine and Foundations of Medicine, we are collaborating on a research study designed to increase our understanding of the mechanisms and causes of Alzheimer’s disease at the molecular level. This study is funded by the Alzheimer’s Foundation of America.

Aaron Pinkhasov, MD, chair of the Department of Psychiatry, is the principal investigator on the clinical aspect of the study responsible for recruitment and evaluation of patients; Allison B. Reiss, MD, is the principal investigator directing the laboratory studies.

Our strategy is to uncover the early abnormalities in nerve function that occur long before symptoms of Alzheimer’s disease appear so that we can design and test potential new corrective treatments to preserve cognitive abilities.

Recent Publications

Learn more about research led by Department of Psychiatry investigators by reading their latest papers.

Ding H … Kasselman LJ. Plants, plants, and more plants: Plant-derived nutrients and their protective roles in cognitive function, Alzheimer's disease, and other dementias. Medicina. 2022. DOI.

Pinkhasov A … Peltier MR. The effect of abuse and mistreatment on healthcare providers (TEAM): A survey assessing the prevalence of aggression from patients and their families and its impact. J Occup Environ Med. 2022. DOI.

Rauchman SH … Reiss AB. Mild-to-moderate traumatic brain injury: A review with focus on the visual system. Neurol Int. 2022. DOI.

Reiss AB … De Leon J. The role of mitochondrial dysfunction in Alzheimer's disease: A potential pathway to treatment. Exp Gerontol. 2022. DOI.

Kasselman LJ … Reiss AB. Cognitive changes mediated by adenosine receptor blockade in a resveratrol-treated atherosclerosis-prone lupus mouse model. J Trad Comp Med. 2022. DOI.

Rauchman SH … Reiss AB. Ongoing use of SSRIs does not alter outcome in hospitalized COVID-19 patients: A retrospective analysis. J Clin Med. 2022. DOI.

Reiss AB … Pinkhasov A. Tau and Alzheimer’s disease: Molecular mechanisms and treatment approaches. SN Comprehensive Clinical Medicine. 2021. DOI.

Pinkhasov A … Fiedorowicz JG. Management of SIADH-related hyponatremia due to psychotropic medications—An expert consensus from the Association of Medicine and Psychiatry. J Psychosom Res. 2021. DOI.

Reiss AB … Katz AE. Prostate cancer treatment and the relationship of androgen deprivation therapy to cognitive function. Clin Transl Oncol. 2021. DOI.

Pinkhasov A … Lam S. Effect of low dose haloperidol and quetiapine on QTc interval in hospitalized elderly patients with delirium. J Phar Prac. 2021. DOI.